There are currently two effective techniques for the treatment of Barrett's esophagus with high-grade dysplasia: radiofrequency and/or mucosectomy.

Radiofrequency is a method which consists of applying radiofrequency energy through electrodes under endoscopic vision with the aim that the mucosa is regenerated by normal cells and Barrett's mucosa is eliminated and with it the risk of esophageal cancer.

Mucosectomy or endoscopic resection of the mucosa is the method that allows us to extract superficial lesions en bloc to obtain a complete histological assessment.  Therefore, diagnosis and therapeutic decisions can be significantly modified.

Radiofrequency can be combined with endoscopic resection of the mucosa if visible lesions are observed.  To a large extent, this technique has successfully replaced surgery, which consists of removing the esophagus, which entails great percentage of complications.